Journal article
DISTINCT ETIOLOGICAL INFLUENCES on OBSESSIVE-COMPULSIVE SYMPTOM DIMENSIONS: A MULTIVARIATE TWIN STUDY
C López-Solà, LF Fontenelle, B Verhulst, MC Neale, JM Menchón, P Alonso, BJ Harrison
Depression and Anxiety | Published : 2016
DOI: 10.1002/da.22455
Abstract
Background Obsessive-compulsive disorder (OCD) is characterized by five major dimensions, including contamination/washing, harm/checking, symmetry/ordering, hoarding, and forbidden thoughts. How these dimensions may relate etiologically to the symptoms of other obsessive-compulsive related disorders (OCRDs) and anxiety disorders (ADs) is not well known. The aim of this study was to examine the genetic and environmental overlap between each major obsessive-compulsive dimension with the symptoms of other OCRDs and ADs. Methods Two thousand four hundred ninety-five twins of both sexes, aged between 18 and 45 years, were recruited from the Australian Twin Registry. Measures used scores on four d..
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Grants
Awarded by National Institutes of Health
Funding Acknowledgements
Contract grant sponsor: The University of Melbourne; Contract grant sponsor: National Health and Medical Research Council of Australia (NHMRC) Clinical Career Development Fellowship; Contract grant number: 628509; Contract grant sponsor: Spanish Ministry of Education, Culture and Sport; Contract grant number: FPU12/01636; Contract grant sponsor: NIDA; Contract grant number: DA-026119; Contract grant sponsor: Instituto de Salud Carlos III cofunded by FEDER funds/European Regional Development Fund (ERDF) - a way to build Europe. Contract numbers: ISCCIII-PI13/01958 and PI14/00413; Contract grant sponsor: National Health and Medical Research Council; Contract grant number: 628911.